Name: Ruben Dries, PhD
Department: Department of Medicine, Sections of Hematology & Medical Oncology and Computational Biomedicine. Associate Member, Center for Regenerative Medicine (CReM)
Research Focus: I study how individual cancer cells make decisions by looking at how they communicate with other cells and their environment. By using spatial technologies and advanced 3D models, I aim to find new ways to improve cancer treatments and patients' quality of life.
Why
BMC: BMC's population of patients has historically been excluded from opportunities in medicine and science, and the work that we are doing here can have a real impact on those communities. The diversity in genes and backgrounds at BMC can also help us better understand individual differences in diagnosis and prognosis, which can help us improve health outcomes for everyone.
Favorite Book: Where the Crawdads Sing by Delia Owens
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Selected Research Publications
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Assoumou, S. A., Alexander, R. N., & Miller, S. E. (2025). "Viral Infections Associated With Injection Drug Use." JAMA.
Cetin, O., Staron, A., Teodorescu, P., Sloan, J. M., Sanchorawala, V., & Szalat, R. (2025). "Bleeding Patterns and Clinical Outcomes in Patients With Systemic AL Amyloidosis-Related Acquired Factor X Deficiency." American Journal of Hematology.
Chen, J. G., Chávez-Fuentes, J. C., O'Brien, M., Xu, J., Ruiz, E. C., Wang, W., Amin, I., Sheridan, J. P., Shin, S. C., Hasyagar, S. V., Sarfraz, I., Guckhool, P., Sistig, A., Jarzabek, V., Yuan, G. C., & Dries, R. (2025). "Giotto Suite: a multiscale and technology-agnostic spatial multiomics analysis ecosystem." Nature Methods.
Hoffman, E. T., et al. (2025). "Aberrant intermediate alveolar epithelial cells promote pathogenic activation of lung fibroblasts in preclinical fibrosis models." Nature Communications.
Kim, J., Cole, M. B., Rosenberg, J., Morris, A., Feinberg, E., & Sheldrick, R. C. (2025). "Integrated Behavioral Health Services and Psychosocial Symptoms in Children." JAMA Network Open.
Joshi, G., Gönenc, A., DiSalvo, M., Faraone, S. V., Ceranoglu, T. A., Yule, A. M., Uchida, M., McDougle, C. J., & Wozniak, J. (2025). "Memantine to Treat Social Impairment in Youths With Autism Spectrum Disorder: A Randomized Clinical Trial." JAMA Network Open.
Ruberg, F. L., et al. (2025). "Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals With Heart Failure." JAMA Cardiology.
Sariahmed, K. Graham, J. E., Herder, M., Morten, C. J. (2025) "Public Sector Innovation and the Constraints of ‘Platform Thinking’: An Account of Johnson & Johnson’s Adenoviral Vector Vaccines". Social Science & Medicine.
Sheehy, S., Aparicio, H. J., Delp, L., Lioutas, V. A., Shulman, J., Xu, N. N., & Rosenberg, L. (2025). "Association of a History of Preterm Delivery With Stroke Risk in the Black Women's Health Study." Neurology.
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